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Related Experiment Video

Updated: Jun 18, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Anaemia control: lessons from the flour fortification programme.

J Sadighi¹, K Mohammad, R Sheikholeslam

¹Institute for Health Sciences Research, Academic Centre for Education, Culture and Research, P.O. Box 13145-483, Tehran, Iran. jsadighi@ihsr.ac.ir

|November 17, 2009

Summary

Iron fortification of flour in Iran reduced iron deficiency but did not significantly change iron-deficiency anaemia prevalence. Anaemia prevalence unexpectedly increased post-intervention in women aged 15-49.

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The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability

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Last Updated: Jun 18, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability

The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability

Published on: April 28, 2022

Area of Science:

Public Health Nutrition
Micronutrient Fortification
Iron Metabolism

Background:

Anaemia is a significant public health concern in Iran.
A national flour fortification program with iron was implemented in two pilot provinces to address this issue.

Purpose of the Study:

To evaluate the effectiveness of the iron fortification program on anaemia and iron deficiency indicators.
To assess the process and coverage of the flour fortification program.

Main Methods:

A before-and-after study design was employed to assess program effectiveness.
Blood hemoglobin and ferritin levels were measured in women aged 15-49 years.
Iron content in flour and bread samples was analyzed to evaluate the fortification process.

Main Results:

The iron fortification program showed a beneficial effect on ferritin levels (indicating reduced iron deficiency).
No significant difference was observed in the prevalence of iron-deficiency anaemia before and after the intervention.
A significant increase in the prevalence of anaemia (low hemoglobin) was noted post-intervention in both provinces.

Conclusions:

Iron fortification can decrease iron deficiency even in populations where anaemia is not solely iron-related.
The program's impact on overall anaemia prevalence requires further investigation, especially in contexts with multifactorial aetiologies.