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Updated: Jun 18, 2026

Organ Ischemia-Reperfusion Injury by Simulating Hemodynamic Changes in Rat Liver Transplant Model
Published on: March 6, 2021
[Accomodation process: ABO-incompatible liver transplantation. Report of one case]
Lorena Castro1, Andrés Yarur, Roberto Segovia
1Departamento de Medicina, Hospital San Borja-Arriarán, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Abstract:
We report a 33 year-old female with a diagnosis of halothane-induce fulminant hepatic failure who was subjected to a liver transplant with an ABO-incompatible graft. The patient received a therapeutic protocol that included total plasma exchange, splenectomy and quadruple immunosuppression. After 5 years, the patient remains asymptomatic and with normal liver enzymes, while she has been treated with low dose of immunosuppressive drugs. This case demonstrates an example of how the immunological process of accommodation opens the possibility of using ABO-incompatible organs as a definitive grafts.
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