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Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
[Sexual exposure to HIV in the French armed forces between 2005 and 2007]
V Pommier de Santi1, L Ollivier, G Texier
1Institut de médecine tropicale du service de santé des armées, IRBA, département d'épidémiologie et santé publique, allée du Médecin-Colonel-Eugène-Jamot, parc du Pharo, BP 60, 13262 Marseille cedex 07, France. pommierdesantiv@imtssa.fr
Epidemiological surveillance of non-occupational HIV exposure in French forces reveals high-risk sexual behaviors. Postexposure prophylaxis has proven effective, with no HIV seroconversions reported since 2000.
Area of Science:
- Public Health
- Epidemiology
- Infectious Disease Surveillance
Background:
- French forces have monitored non-occupational Human Immunodeficiency Virus (HIV) exposure since 2000.
- This surveillance serves as an indirect measure of risky sexual behaviors among military personnel.
Purpose of the Study:
- To analyze trends and characteristics of non-occupational HIV exposure within the French armed forces.
- To evaluate the effectiveness of postexposure prophylaxis (PEP) strategies.
Main Methods:
- Data collected by military physicians from 2005 to 2007 on non-occupational HIV exposures meeting notification criteria.
- Analysis of case demographics, exposure circumstances, condom usage, and PEP prescription rates.
Main Results:
- 2241 cases filed between 2005-2007; annual incidence 214.3/100,000.
- Exposures predominantly in men (99.2%), overseas (92.9%), with sex workers (66.7%).
- Inadequate condom use reported in 15.5%; PEP prescribed in 70.5% of cases.
Conclusions:
- Most reported sexual exposures in French armed forces carry a high HIV transmission risk.
- No HIV seroconversions reported post-PEP since surveillance began in 2000.
- The strategy for non-occupational PEP is considered effective and not in question.
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