Related Experiment Video
Updated: May 5, 2026

Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment
Published on: July 7, 2023
Telephone-delivered collaborative care for treating post-CABG depression: a randomized controlled trial.
Bruce L Rollman1, Bea Herbeck Belnap, Michelle S LeMenager
1Division of General Internal Medicine, Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. rollmanbl@upmc.edu
Telephone-delivered collaborative care significantly improved mental health-related quality of life, physical functioning, and mood symptoms in patients after coronary artery bypass graft (CABG) surgery compared to usual care.
Area of Science:
- Cardiology
- Psychiatry
- Health Services Research
Background:
- Depression is a common complication following coronary artery bypass graft (CABG) surgery, negatively impacting clinical outcomes.
- Identifying effective interventions for post-CABG depression is crucial for improving patient recovery and well-being.
Purpose of the Study:
- To evaluate the efficacy of a telephone-delivered collaborative care model for treating depression in patients post-CABG.
- To compare the outcomes of collaborative care against usual physician care for this patient population.
Main Methods:
- A single-blind effectiveness trial involving 302 post-CABG patients with depression across 7 hospitals.
- Intervention group received 8 months of telephone-delivered collaborative care managed by nurses, supervised by physicians.
- Outcomes measured included mental and physical health-related quality of life (HRQL), mood symptoms, and functional status.
Main Results:
- Collaborative care patients showed significant improvements in mental HRQL, physical functioning, and mood symptoms (Hamilton Rating Scale for Depression).
- A greater proportion of intervention patients experienced a 50% or greater reduction in depression symptoms.
- Men with depression particularly benefited from the intervention, showing substantial gains in mental HRQL.
Conclusions:
- Telephone-delivered collaborative care is an effective strategy for managing post-CABG depression.
- This intervention leads to enhanced HRQL, improved physical functioning, and reduced mood symptoms at 8-month follow-up.
- The findings support the integration of collaborative care models into routine post-surgical care pathways.
More Related Videos
08:53Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
Published on: June 6, 2025
12:43Robotically Delivered fMRI-Guided Personalized Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression
Published on: April 10, 2026
Related Concept Videos
Long-term Depression
Long-term Depression
Calcium Ion Concentration Mechanism
If over...
Depression: Overview
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care
Cognitive Therapy