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Updated: Jun 18, 2026

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children
Published on: August 19, 2020
Measuring tissue oxygen saturation via spectrometer in children
Ran D Goldman1, Aly Shah Aziz, Linda Marques
1Pediatric Research in Emergency Therapeutics Program, Division of Pediatric Emergency Medicine, BC Children's Hospital, Canada. rgoldman@cw.bc.ca
Near-infrared spectroscopy (NIRS) effectively measures tissue oxygen saturation (StO2) in children. Bicep and deltoid muscles are optimal measurement sites, showing reliable StO2 readings with minimal variation.
Area of Science:
- Biomedical Engineering
- Medical Devices
- Pediatric Medicine
Background:
- Near-infrared spectroscopy (NIRS) offers a noninvasive method for monitoring tissue oxygen saturation (StO2).
- Evaluating new NIRS devices is crucial for clinical application in diverse patient populations.
Purpose of the Study:
- To assess the performance of the InSpectra near-infrared tissue spectrometer in pediatric patients.
- To identify optimal body locations for measuring tissue oxygen saturation (StO2) in children.
Main Methods:
- A prospective study was conducted in a pediatric emergency department.
- Tissue oxygen saturation (StO2) was measured using a 25-mm probe on various body sites in children aged 0-17 years without respiratory distress.
- Measurements included deltoid muscle, thenar eminence, forearm, calf, bicep, and tricep.
Main Results:
- 310 children participated; average StO2 was highest on the bicep (84%) and deltoid (83.5%) muscles.
- Lower StO2 variation was observed on the bicep, deltoid, and thenar muscles.
- Age and weight correlated with StO2 on the thenar eminence; febrile children showed lower thenar StO2.
Conclusions:
- Bicep and deltoid muscles are recommended for pediatric StO2 measurement with the 25-mm transducer.
- Thenar eminence measurements in children yield variable results influenced by age, weight, and fever, unlike in adults.
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