Related Experiment Video
Updated: Jun 18, 2026
The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
Published on: June 1, 2019
Coexisting tattoo pigment and metastatic melanoma in the same sentinel lymph node
Adnan A Jaigirdar1, Michael W Yeh, Emile Sharifi
1Departments of Surgery and Pathology, University of California, San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center, UCSF Medical Center at Mount Zion, San Francisco, CA 94115, USA.
Background:
The principle of sentinel lymph node states that metastatic melanoma spreads in a predictable sequential fashion from the primary site to the regional lymph node basin.
Objective And Conclusion:
Reports show that melanoma and tattoo pigment can be in the same regional lymph node basin on gross evaluation. We present two cases of melanoma arising within the setting of a tattoo where the sentinel lymph node contained both pigmented histiocytes and metastatic melanoma on gross inspection and histopathology.
