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Updated: Jun 18, 2026
Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
Rapid visual recovery and long-term intraocular pressure control after donor scleral patch grafting for
1Asheville Eye Medical and Surgical Associates, Asheville, and Department of Ophthalmology, Duke University, Durham, North Carolina; and *Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, U.S.A.
Purpose:
To report on a 21-year-old man who had persistent hypotony maculopathy eight months after trabeculectomy with mitomycin C.
Methods:
He was treated by excising the filtering bleb, placing a donor scleral patch graft over the trabeculectomy site, and bringing conjunctiva superior to the previous bleb over the patch graft.
Results:
He had rapid resolution of his hypotony accompanied by an increase in visual acuity from 4/200 preoperatively to 20/80 at one day, and 20/20 at three months postoperatively. He also established and maintained a filtration bleb which kept his intraocular pressure in the mid teens without the use of medication.
Conclusion:
Scleral patch grafting may provide rapid resolution of visual loss secondary to hypotony maculopathy.
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