Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Parathyroid Glands

The Parathyroid Glands

The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

Synthesis and Functions of Calcitonin

Synthesis and Functions of Calcitonin

Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...

Hormones and Bone Tissue

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...

Graves Disease II: Pathophysiology

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...

Skeleton and Calcium Homeostasis

Skeleton and Calcium Homeostasis

Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Gender ratio trends over time in multiple sclerosis patients from Argentina.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2017

Same author

Primary angiitis of the Central Nervous Sistem: 25 years of follow-up and mild motor sequelae.

Neurologia·2016

Same author

Disease onset in familial and sporadic multiple sclerosis in Argentina.

Multiple sclerosis and related disorders·2016

Same author

Recurrent diaphoresis, acute confusional state, and pleural mesothelioma.

Neurologia (Barcelona, Spain)·2016

Same author

Oxidative stress in neurological disease: is it the cause, consequence, or trigger of a chronic progressive form?

Neurologia (Barcelona, Spain)·2015

Same author

Asymptomatic colpocephaly and partial agenesis of corpus callosum.

Neurologia (Barcelona, Spain)·2014

Search research articles

Related Experiment Video

Updated: Jun 18, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

[Asymptomatic encephalic calcifications in postsurgical hypoparathyroidism].

G Abiusi¹, R O Domínguez, M Parada Marcilla

¹Servicio de Neurología, Hospital Municipal de Boulogne, Buenos Aires, Argentina.

Neurologia (Barcelona, Spain)

|November 19, 2009

Summary

Hypoparathyroidism (HP) after thyroidectomy can lead to encephalic calcifications (EC) even without symptoms. These calcifications may be underdiagnosed in post-surgical HP patients due to their asymptomatic nature.

Related Experiment Videos

Last Updated: Jun 18, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

Area of Science:

Neurology
Endocrinology
Radiology

Context:

Encephalic calcifications (EC) are common findings on CT scans with diverse etiologies.
Post-thyroidectomy hypoparathyroidism (HP) is a known complication.
The relationship between subclinical HP, EC, and clinical manifestations remains incompletely understood.

Purpose:

To investigate the prevalence and clinical presentation of EC in patients with a history of thyroidectomy and subsequent hypoparathyroidism.
To analyze the correlation between EC, biochemical markers (calcium, parathormone, phosphorus), and neurological/cognitive status.

Summary:

A cohort of 38 women with prior thyroidectomy were evaluated for hypoparathyroidism and encephalic calcifications.
Six patients (15%) had HP, with five (13%) exhibiting EC, primarily affecting basal ganglia and white matter.
Despite EC presence, neurological and cognitive assessments were normal, with reduced serum calcium and parathormone, and elevated phosphorus.

Impact:

Suggests that EC may be underdiagnosed in asymptomatic post-surgical HP.
Highlights the potential for EC development even with moderate reductions in calcium and parathormone.
Underscores the need for neuroimaging in patients with a history of thyroidectomy and suspected HP.