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A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging
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NIR dyes for bioimaging applications
Jorge O Escobedo1, Oleksandr Rusin, Soojin Lim
1Department of Chemistry, Portland State University, Portland, OR 97207, USA.
Current Opinion in Chemical Biology
|November 21, 2009
Abstract:
Fluorescent dyes based on small organic molecules that function in the near infrared (NIR) region are of great current interest in chemical biology. They allow for imaging with minimal autofluorescence from biological samples, reduced light scattering, and high tissue penetration. Herein, examples of ongoing NIR fluorophore design strategies as well as their properties and anticipated applications relevant to the bioimaging are presented.
