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Related Experiment Video

Updated: Jun 11, 2026

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
12:20

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Published on: July 22, 2013

Carbon nanotube-enhanced cell electropermeabilisation.

Vittoria Raffa1, Gianni Ciofani, Orazio Vittorio

  • 1Medical Science Lab, Scuola Superiore Sant'Anna, Piazza Martiri della Libertà 33, Pisa, Italy. s.raffa@sssup.it

Bioelectrochemistry (Amsterdam, Netherlands)
|November 21, 2009
PubMed
Summary
This summary is machine-generated.

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This study introduces carbon nanotubes (CNTs) to reduce high voltages needed for cell electro-permeabilisation. This CNT-enhanced method achieves over 80% efficiency at below 50V/cm, minimizing cell death for clinical applications.

Area of Science:

  • Biotechnology
  • Materials Science
  • Cell Biology

Background:

  • Controlled electric fields are used for cell permeabilisation to enhance molecular uptake.
  • High voltages required for traditional electro-permeabilisation cause significant cell death, limiting clinical use.

Purpose of the Study:

  • To present a novel method for cell electro-permeabilisation using carbon nanotubes (CNTs) and static electric fields.
  • To reduce the high voltages typically required for effective and repairable cell electro-permeabilisation.

Main Methods:

  • Utilized multiwall carbon nanotubes (MWCNTs) in conjunction with external static electric fields.
  • Investigated the dielectric response of MWCNTs to applied electric fields to explain the mechanism.
  • Experimentally validated the CNT-enhanced electro-permeabilisation process.

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Related Experiment Videos

Last Updated: Jun 11, 2026

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
12:20

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Published on: July 22, 2013

Fabrication of Low Temperature Carbon Nanotube Vertical Interconnects Compatible with Semiconductor Technology
09:20

Fabrication of Low Temperature Carbon Nanotube Vertical Interconnects Compatible with Semiconductor Technology

Published on: December 7, 2015

Precision Milling of Carbon Nanotube Forests Using Low Pressure Scanning Electron Microscopy
08:10

Precision Milling of Carbon Nanotube Forests Using Low Pressure Scanning Electron Microscopy

Published on: February 5, 2017

Main Results:

  • The CNT-enhanced method significantly lowers the required electric field voltage to below 50V/cm.
  • Achieved a cell electro-permeabilisation efficiency exceeding 80%.
  • Demonstrated repairable cell electro-permeabilisation at reduced voltages.

Conclusions:

  • CNT-enhanced electro-permeabilisation offers a promising approach to overcome the limitations of traditional methods.
  • This technique facilitates efficient and repairable cell permeabilisation with significantly reduced voltage requirements.
  • The findings suggest potential for improved clinical applications of electro-permeabilisation technologies.