Physical and neurodevelopmental evaluation of children adopted from Eastern Europe

Children adopted from Eastern Europe are at risk of prenatal alcohol exposure, consequently at risk of Fetal Alcohol Spectrum Disorders (FASD). To our knowledge, a systematic complete assessment of these disabilities among adoptees from Eastern Europe has not yet been reported.

To assess physical and neurodevelopmental status to identify FASD in children adopted from Eastern Europe.

Cross sectional study at International Adoption Clinic of a paediatric academic hospital. This evaluation was realized according to the 4-Digit Diagnostic Code (4-DDC).

Twenty-nine children were evaluated. Five years after adoption, 7% (N=2) still presented growth delay and 24% (N=7) microcephaly. Facial evaluation demonstrated moderate Fetal Alcohol Syndrome (FAS) features in 7% (N=2) of children. Amiel-Tison Neurological Assessment was non optimal in 46% (N=13/28) of children. Visual-motor perception skills were mainly normal, but 14% (N=4) showed distal somatopraxic problems. Cognition, executive functioning, abstract reasoning and memory were normal. Full scale IQ was 105.5 +/- 13.3; verbal IQ < performance IQ (p<0.005), work memory < short memory (p<0.0001), receptive

In our cohort, the 4-DDC was useful. Systematic and multidisciplinary neurodevelopmental assessment is needed in these adopted children, for an early intervention to prevent secondary disabilities and therefore optimize children's outcome.