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Posterior vitreous contraction after cerebral sinus thrombosis
Liang Xu1, Xi Wei Xie, Jost B Jonas
1Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Schience, Beijing, China.
Summary
Oral hormonal therapy for uterine bleeding may cause cerebral venous sinus thrombosis, leading to headaches and papilledema. Prompt thrombolytic treatment resolved symptoms and improved vision, though some visual complications persisted.
Area of Science:
- Neurology
- Ophthalmology
- Endocrinology
Background:
- Cerebral venous sinus thrombosis (CVST) is a rare but serious condition.
- Oral hormonal therapy is used for dysfunctional uterine bleeding.
Observation:
- A 34-year-old woman developed headaches and papilledema while on oral hormonal therapy.
- Neurological examination indicated cerebral venous sinus thrombosis.
Findings:
- Thrombolytic treatment resolved headaches and right-eye papilledema.
- Visual acuity improved, but left-eye papilledema caused posterior vitreous changes, macular folding, and foveal irregularities.
Implications:
- Hormonal therapy may be a risk factor for CVST.
- Early diagnosis and thrombolytic treatment are crucial for managing CVST and preserving vision.
- Ophthalmological monitoring is essential in patients with CVST and visual disturbances.
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