Spectrally tunable leakage-free gold nanocontainers

Drug delivery with precise spatial and temporal control is of broad current interest in biology and medicine. Despite recent advances achieved by combining drugs or drug carriers with NIR light responsive plasmonic nanomaterials, existing technologies are not capable of preventing drug leakage or degradation. We report a new class of monodisperse gold nanocontainer that can stably encapsulate cargo molecules, yet is compact in size and tunable in spectral responses.