Related Experiment Video
Updated: Jun 18, 2026

08:57
Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
Published on: May 17, 2024
[Hamartomatous and pluritissular tumors]
R H Khonsari1, J Lepourry, P Corre
1Service de chirurgie maxillofaciale et stomatologie, CHU de Nantes, CHU Hôtel-Dieu, 1, place Alexis-Ricordeau, 44000 Nantes, France. roman.khonsari@kcl.ac.uk
Revue De Stomatologie Et De Chirurgie Maxillo-Faciale
|November 26, 2009
Summary
Hamartomas are benign growths of normal cells in the jawbone. Treatment involves surgery for jaw deformities and screening for other tumors.
Area of Science:
- Oral and Maxillofacial Surgery
- Pathology
- Oncology
Context:
- Hamartomas are benign tumors arising from normal tissue components.
- Maxillofacial hamartomas present unique challenges due to their location and potential for disfigurement.
- These tumors exhibit variable histology despite their benign nature.
Purpose:
- To define hamartomas and their characteristics within the maxilla and mandible.
- To outline the therapeutic principles for managing maxillofacial hamartomas.
- To emphasize the importance of screening for associated extra-facial tumors.
Summary:
- Hamartomas represent benign proliferations of indigenous cells, often with altered tissue architecture.
- Maxillofacial hamartomas require surgical intervention to address mass effects and cosmetic deformities.
- Mandatory screening for systemic tumors is crucial due to potential associations.
Impact:
- Highlights the dual approach of surgical management and oncological surveillance for maxillofacial hamartomas.
- Improves understanding of the heterogeneity and clinical behavior of these rare jaw tumors.
- Underscores the significance of a comprehensive diagnostic and therapeutic strategy.

