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Updated: Jun 18, 2026

Modification of the Treatment Methods for Wasting Marmoset Syndrome with Tranexamic Acid and Supportive Measures
Published on: July 12, 2024
[Mallory-Weiss syndrome: diagnosis and treatment]
Stéphane Lecleire1, Michel Antonietti, Philippe Ducrotté
1Unité d'endoscopie digestive, Département d'hépato-gastroentérologie et nutrition, Rouen Cedex, France. stephane.lecleire@chu-rouen.fr
Abstract:
Mallory-Weiss syndrome is relatively common and is involved in 3 to 10% of cases of upper gastrointestinal bleeding. Most of the time, the hemorrhage is mild and stops spontaneously. Clinical suspicion requires confirmation by an upper gastrointestinal endoscopy, which must be performed rapidly after the first hematemesis. Mallory-Weiss syndrome is diagnosed when it shows a longitudinal mucosal tear at the esophagogastric junction. Patients with active bleeding or signs of recent bleeding at endoscopy need immediate endoscopic treatment for hemostasis. Band ligation seems to be the most efficient procedure for primary hemostasis and for preventing recurrent bleeding. The use of proton pump inhibitors and antiemetics seems logical in all cases, although nothing in the literature demonstrates their efficacy.
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