Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Fetal Circulation

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Whole Metagenomic Profiling Identifies a Gut Microbial Signature for Chronic Pancreatitis via Machine Learning.

Pancreas·2026

Same author

CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer.

Cancer research·2023

Same author

Assessment of the Murine Tumor Microenvironment by Multiplex Immunofluorescence.

Methods in molecular biology (Clifton, N.J.)·2022

Same author

Interleukin-17-induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer.

The Journal of experimental medicine·2020

Same author

Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma.

British journal of cancer·2019

Same author

Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes.

Cell·2019

Search research articles

Related Experiment Video

Updated: Jun 18, 2026

Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation

Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation

Published on: January 7, 2021

A method for subsample fetal heart rate estimation under noisy conditions.

Ismet Sahin¹, Nuri Yilmazer, Marwan A Simaan

¹Department of Biomedical Informatics, University of Pittsburgh, PA 15260, USA. isahin@gmail.com

IEEE Transactions on Bio-Medical Engineering

|November 26, 2009

Summary

This study introduces a novel method for estimating the fundamental period in fetal electrocardiogram (ECG) waveforms. This new approach accurately determines fetal well-being indicators like hypoxia and acidemia, even in noisy conditions.

More Related Videos

In utero Measurement of Heart Rate in Mouse by Noninvasive M-mode Echocardiography

In utero Measurement of Heart Rate in Mouse by Noninvasive M-mode Echocardiography

Published on: November 22, 2013

BrainBeats as an Open-Source EEGLAB Plugin to Jointly Analyze EEG and Cardiovascular Signals

BrainBeats as an Open-Source EEGLAB Plugin to Jointly Analyze EEG and Cardiovascular Signals

Published on: April 26, 2024

Related Experiment Videos

Last Updated: Jun 18, 2026

Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation

Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation

Published on: January 7, 2021

In utero Measurement of Heart Rate in Mouse by Noninvasive M-mode Echocardiography

In utero Measurement of Heart Rate in Mouse by Noninvasive M-mode Echocardiography

Published on: November 22, 2013

BrainBeats as an Open-Source EEGLAB Plugin to Jointly Analyze EEG and Cardiovascular Signals

BrainBeats as an Open-Source EEGLAB Plugin to Jointly Analyze EEG and Cardiovascular Signals

Published on: April 26, 2024

Area of Science:

Biomedical Engineering
Signal Processing
Fetal Monitoring

Background:

The fundamental period of fetal ECG (fECG) waveforms provides critical insights into fetal physiological status, including potential hypoxia and acidemia.
Accurate estimation of this period is essential for effective prenatal monitoring and timely clinical intervention.

Purpose of the Study:

To develop and validate a new, highly accurate method for estimating the fundamental period of fECG waveforms.
To enable precise fECG analysis, particularly under noisy conditions and with low sampling rates.

Main Methods:

A novel approach based on minimizing a cost function derived from the discrete Fourier transform (DFT) of fECG waveforms and their shifted versions.
The method identifies the optimal cosine waveform that best matches the fECG power spectrum for period estimation.
Subsample precision estimation techniques are incorporated for enhanced accuracy, especially during long-term, low-sampling-rate monitoring.

Main Results:

The proposed method demonstrates highly accurate fECG fundamental period estimation for both simulated and real-world data.
Performance comparisons show superior accuracy compared to traditional Cepstrum and average magnitude difference function methods.
Effective performance is maintained even under noisy conditions and across different stages of gestation.

Conclusions:

The developed method offers a significant advancement in fECG analysis for assessing fetal health.
Its accuracy and robustness make it a valuable tool for clinical applications in fetal monitoring.
The technique provides reliable period estimation, aiding in the early detection of fetal distress.