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An Optimized Hemagglutination Inhibition (HI) Assay to Quantify Influenza-specific Antibody Titers
Published on: December 1, 2017
Trial of influenza HA vaccination for healthcare workers in consecutive years
Yukihiko Fujita1, Tsuyoshi Okada, Hideo Mugishima
1Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 173-8610, Japan. yfujita@med.nihon-u.ac.jp
Abstract:
We investigated the trial of the influenza HA vaccination for healthcare workers in 2 consecutive years at Nihon University Itabashi Hospital. The vaccination rate increased significantly (P<0.01) from the first season to the second season. The number of missed working days in the vaccinated group was significantly lower (P<0.01) than that in the unvaccinated group in a mild-pandemic year. Furthermore, the relative risk of infection was 0.53 and the effectiveness rate of the vaccine was 46.8%. Absenteeism and influenza infection rates were also significantly lower in the vaccinated group. This study may support the possibility of influenza vaccination for healthcare workers to prevent the outbreak of influenza in hospitals.
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