T-cell immune monitoring in organ transplantation

Rajani Dinavahi1, Peter S Heeger

  • 1Division of Nephrology, Mount Sinai School of Medicine, Recanati/Miller Transplantation Institute, New York, NY 10029, USA. peter.heeger@mssm.edu

Transplantation
|November 26, 2009
PubMed

Chronic allograft injury remains the leading cause of graft loss despite improvements in immunosuppression, clinical risk stratification, and state-of-the-art antibody testing. Emerging results indicate that T-cell immune monitoring by cytokine enzyme-linked immunosorbent spot, as part of a comprehensive risk assessment platform, has the potential to guide decision making and improve outcomes after transplantation.