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Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Complications of Diabetes Mellitus01:22

Complications of Diabetes Mellitus

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

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Related Experiment Video

Updated: Jun 18, 2026

Modeling Cataract Surgery in Mice
05:19

Modeling Cataract Surgery in Mice

Published on: December 1, 2023

Cataract surgery and diabetes.

Ankoor S Shah1, Sherleen H Chen

  • 1Eye Trauma Service, Department of Ophthalmology, Harvard Medical School, Massachusetts Eye & Ear Infirmary, Boston, Massachusetts 02114, USA.

Current Opinion in Ophthalmology
|November 26, 2009
PubMed
Summary
This summary is machine-generated.

Cataract surgery does not universally worsen diabetic retinopathy. Interventions like bevacizumab and triamcinolone may help specific diabetic patients, while optimal timing for panretinal photocoagulation needs further study.

Related Experiment Videos

Last Updated: Jun 18, 2026

Modeling Cataract Surgery in Mice
05:19

Modeling Cataract Surgery in Mice

Published on: December 1, 2023

Area of Science:

  • Ophthalmology
  • Diabetic Retinopathy Research
  • Cataract Surgery Outcomes

Background:

  • Diabetic patients undergoing cataract surgery face risks of retinal disease progression.
  • Minimizing progression of diabetic retinopathy and macular edema is a key concern.

Purpose of the Study:

  • Review evidence on diabetic retinal disease progression post-cataract surgery.
  • Critically analyze interventions aimed at mitigating this progression.

Main Methods:

  • Review of recent studies on interventions for diabetic patients undergoing cataract surgery.
  • Analysis of peri-operative bevacizumab, triamcinolone, and post-surgery panretinal photocoagulation (PRP).

Main Results:

  • Bevacizumab and triamcinolone show promising results but with variable criteria and small sample sizes.
  • Post-surgery PRP improved outcomes in diabetics with severe retinopathy up to one year.
  • Phacoemulsification surgery does not universally worsen retinopathy or macular edema.

Conclusions:

  • Peri-operative triamcinolone and bevacizumab may reduce progression of diabetic macular edema and retinopathy in select patients.
  • The generalized conclusion of cataract surgery worsening diabetic retinopathy is not supported.
  • Optimal timing of PRP relative to cataract surgery requires further investigation.