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Lighting up neural networks using a new generation of genetically encoded calcium sensors
Christian D Wilms1, Michael Häusser
1Wolfson Institute for Biomedical Research and Department of Neuroscience, Physiology and Pharmacology, University College London, UK.
Nature Methods
|November 26, 2009
Abstract:
Two improved genetically encoded calcium indicators-based on structure-guided sensor design or on precise subcellular targeting to presynaptic boutons-allow single spikes to be detected in genetically defined populations of neurons and synapses in vivo.
