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A case of eosinophilic orbital myositis associated with CSS
Tomoko Fujii1, Masataro Norizuki, Tatsuo Kobayashi
1Department of Rheumatology, Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba, 296-8602, Japan. tofujii-tky@umin.net
Modern Rheumatology
|November 26, 2009
Summary
We describe a rare case of eosinophilic orbital myositis linked to Churg-Strauss syndrome. Prompt corticosteroid treatment led to rapid symptom improvement in this patient.
Area of Science:
- Ophthalmology
- Rheumatology
- Neurology
Background:
- Churg-Strauss syndrome, also known as eosinophilic granulomatosis with polyangiitis, is a rare systemic vasculitis.
- Orbital myositis, an inflammation of the extraocular muscles, can present with various symptoms including diplopia.
Observation:
- A 56-year-old male with a history of chronic sinusitis and allergic rhinitis presented with fever, facial swelling, diplopia, and marked eosinophilia.
- Gadolinium-enhanced FST1WI of the orbits revealed characteristic findings suggestive of myositis.
- Skeletal muscle biopsy confirmed the presence of eosinophilic infiltration.
Findings:
- The patient was diagnosed with eosinophilic orbital myositis associated with Churg-Strauss syndrome.
- Treatment with oral corticosteroids resulted in a rapid and significant improvement of his clinical symptoms.
Implications:
- This case highlights the importance of considering eosinophilic orbital myositis in patients with Churg-Strauss syndrome presenting with ocular symptoms.
- Early diagnosis and treatment with corticosteroids can lead to favorable outcomes.
- Further research may elucidate the specific mechanisms linking orbital myositis and Churg-Strauss syndrome.
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