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Three-Dimensionally Printed Microfluidic Cross-flow System for Ultrafiltration/Nanofiltration Membrane Performance Testing
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Mimic of a large-scale diafiltration process by using ultra scale-down rotating disc filter

Guijun Ma1, Jean Aucamp, Spyridon Gerontas

  • 1Dept. of Biochemical Engineering, The Advanced Centre for Biochemical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK.

Biotechnology Progress
|November 26, 2009
PubMed
Summary

This study introduces an ultra-scale-down rotating disc filter method to accurately predict large-scale filtration performance using minimal sample volumes. The novel approach simplifies operations while maintaining crossflow mimicry for reliable process development.

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