[Target-oriented infusion therapy in patients during myocardial revascularization]

Area of Science:

• Cardiology
• Anesthesiology
• Critical Care Medicine

Context:

• Myocardial revascularization on a working heart requires precise fluid management.
• Standard infusion therapy relies on general hemodynamic parameters.
• Individualized fluid management strategies may improve patient outcomes.

Purpose:

• To evaluate the efficacy of goal-oriented infusion therapy in maintaining optimal preload during myocardial revascularization.
• To compare hemodynamic stability and resource utilization between goal-oriented and standard infusion therapy.

Summary:

• Forty-seven patients with coronary heart disease were divided into two groups: standard infusion therapy (control) and goal-oriented infusion therapy.
• The goal-oriented group focused on maintaining the individual optimal preload (global end-diastolic volume index) using passive leg raising tests.
• This individualized approach aimed to optimize fluid administration based on preload responsiveness.

Impact:

• Goal-oriented infusion therapy significantly minimized hemodynamic disorders during surgery.
• It led to a reduced need for cardiotonic agents.
• The duration of artificial ventilation was also decreased in the goal-oriented group.