Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Whole Body Regeneration01:33

Whole Body Regeneration

Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential; even...
Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A tissue engineering approach to regenerate the cranial suture skeletal stem cell niche with a multicompartment biomaterial scaffold.

Bone research·2026
Same author

<i>Gli1<sup>+</sup></i> Cells Exhibit Clonogenicity and Slow-Cycling Features at the Temporomandibular Joint (TMJ) Enthesis-Condyle Interface.

International journal of molecular sciences·2026
Same author

Two-step Gelatin Embedding Preserves Fibrocartilage Morphology, Enthesis, and Cartilage Stain of Bone Joints.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society·2026
Same author

Nanofibrous scaffolds for bone and cartilage regeneration.

Applied physics reviews·2026
Same author

Role of FGF2 in promoting osteogenic differentiation for craniofacial bone regeneration.

Regenerative engineering and translational medicine·2026
Same author

New block copolymers to form nanofibers with superior mechanical properties and to conjugate signaling molecules directing tissue regeneration.

Materials today (Kidlington, England)·2026
Same journal

Shear-Induced CROSS (Cellular RedOx Spreading Shield) Assembly Sustains Neurotrophic Extracellular Vesicle Production for Functional Neural Networks.

Advanced functional materials·2026
Same journal

Buckling-Resistant and Trace-Stacked (BRATS) Design Enables Aid-Free Implantation of Flexible Multielectrode Array with Minimized Inflammatory Tissue Response.

Advanced functional materials·2026
Same journal

Rationally designed anisotropic and auxetic hydrogel patches for adaptation to dynamic organs.

Advanced functional materials·2026
Same journal

Benchtop Fabrication and Integration of Laser-Induced Graphene Strain Gauges and Stimulation Electrodes in Muscle on a Chip Devices.

Advanced functional materials·2026
Same journal

Controlling 3D Contractility via Engineered Fibrous Hydrogel Composites.

Advanced functional materials·2026
Same journal

Cardiac-Derived ECM Microspheres for Enhanced hiPSC-CMs Maturation.

Advanced functional materials·2026
See all related articles

Related Experiment Video

Updated: Jun 18, 2026

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
10:45

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling

Published on: May 31, 2017

Nanostructured Biomaterials for Regeneration.

Guobao Wei1, Peter X Ma

  • 1Department of Biomedical Engineering, University of Michigan.

Advanced Functional Materials
|December 1, 2009
PubMed
Summary
This summary is machine-generated.

Nanostructured biomaterials mimic the natural extracellular matrix (ECM) to guide tissue regeneration. Incorporating nano-scaled drug delivery into these scaffolds enhances healing and cellular responses for regenerative medicine applications.

More Related Videos

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration
11:42

Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration

Published on: September 12, 2014

Related Experiment Videos

Last Updated: Jun 18, 2026

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
10:45

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling

Published on: May 31, 2017

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration
11:42

Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration

Published on: September 12, 2014

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Nanotechnology

Background:

  • Biomaterials, particularly scaffolds, are crucial in regenerative medicine for tissue repair and replacement.
  • Effective scaffolds should emulate the nanoscale features of the extracellular matrix (ECM) and promote natural healing processes.
  • Nanostructured materials offer unique advantages in mimicking biological environments and guiding cellular behavior.

Purpose of the Study:

  • To review fabrication and modification technologies for advanced biomaterial scaffolds.
  • To explore the role of nanofibrous, nanocomposite, and nanostructured scaffolds in tissue regeneration.
  • To highlight the integration of drug delivery systems within these scaffolds.

Main Methods:

  • Review of current literature on scaffold fabrication and modification techniques.
  • Analysis of studies focusing on ECM-mimicking nanostructured biomaterials.
  • Examination of nano-scaled drug delivery systems incorporated into 3D scaffolds.

Main Results:

  • Nanostructured biomaterials effectively regulate cellular responses like attachment, proliferation, differentiation, and matrix deposition.
  • ECM-mimicking scaffolds demonstrate significant potential in guiding tissue formation.
  • Incorporation of nano-drug delivery systems into scaffolds enhances regenerative capacity.

Conclusions:

  • Nanostructured biomaterials are a rapidly advancing field with significant implications for regenerative medicine.
  • These materials provide novel technological solutions for tissue regeneration and repair.
  • The synergy between nanostructure and drug delivery offers powerful tools for therapeutic applications.