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Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow
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[Study and evaluation on hemocompatibility of biomaterials]

Lifeng Yang1, Jianxia Xu, Tingfei Xi

  • 1Whenzhou Medical College, Wenzhou 325035, China.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi
|December 2, 2009
PubMed

Hemocompatibility is an important component of biocompatibility; it reflects the degree of interaction between material and blood. Hemocompatibility is multifaceted, so that the material's impact on the blood and the underlying mechanism are very complicated. This article presents a review of researches probing the impact of material on blood via contact activation and plasma protein adsorption; via the platelet activated and the formation of thrombin; via the complement system activated and the activation of leukocytes as well as other mechanisms of hemolysis. The current methods for evaluation and the future trend of development are also introduced.

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