Related Experiment Video
Updated: Jun 18, 2026

11:32
Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
A rare complication of a pneumococcal pneumonia
M J van Apeldoorn1, E Ozdas, F Nijland
1Department of internal medicine, Sint Lucas Andreas Hospital, Amsterdam, the Netherlands.
Summary
This case report details a rare instance of pyopneumopericarditis, a serious condition involving pus and air in the pericardial sac, developing as a complication of pneumonia.
Area of Science:
- Cardiology
- Infectious Diseases
- Pulmonology
Background:
- Pyopneumopericarditis is a rare and life-threatening condition.
- It involves the accumulation of pus and air within the pericardial sac.
- This complication is seldom observed in contemporary medical practice.
Purpose of the Study:
- To report a rare case of pyopneumopericarditis secondary to pneumonia.
- To highlight the diagnostic and management challenges associated with this rare complication.
- To emphasize the importance of considering uncommon diagnoses in severe infections.
Main Methods:
- Case report presentation.
- Review of clinical presentation, diagnostic findings, and treatment.
- Discussion of the pathophysiology linking pneumonia to pyopneumopericarditis.
Main Results:
- The patient developed pyopneumopericarditis as a direct consequence of pneumonia.
- Successful management of the condition was achieved.
- The case underscores the potential for severe intrathoracic complications from pneumonia.
Conclusions:
- Pyopneumopericarditis, though rare, can arise from pneumonia.
- Prompt recognition and intervention are crucial for favorable outcomes.
- This case contributes to the limited literature on this unusual clinical entity.
Related Concept Videos
Pneumonia I: Introduction
Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Pneumonia I: Introduction
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia III: Complications and Assessment
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Atypical Pneumonia
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pneumonia II: Pathophysiology
The pathophysiology of pneumonia involves the following steps:
Pneumothorax-I
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.

