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Published on: March 28, 2025
Treatment of intermittent obstructive hydrocephalus secondary to a choroid plexus cyst
Tanya Z Filardi1, Laura Finn, Patrik Gabikian
1Department of Neurological Surgery, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington 98105, USA. tanya.filardi@seattlechildrens.org
Insights
A choroid plexus cyst caused intermittent obstructive hydrocephalus in an infant. Endoscopic cyst fenestration resolved the condition, offering a unique case study for pediatric neurosurgery.
Area of Science:
- Pediatric Neurosurgery
- Neuroimaging
- Congenital Neurological Disorders
Background:
- Hydrocephalus in infants can arise from various causes, including intraventricular cysts.
- Choroid plexus cysts are common but rarely cause significant obstructive hydrocephalus.
Observation:
- An 11-week-old infant presented with acute symptoms of hydrocephalus, including vomiting and lethargy.
- Initial CT scan confirmed hydrocephalus, which transiently resolved.
- MRI revealed intermittent third ventricular obstruction by a choroid plexus cyst.
Findings:
- The choroid plexus cyst intermittently obstructed the third ventricle, leading to obstructive hydrocephalus.
- Endoscopic fenestration of the cyst successfully treated the condition.
Implications:
- This case highlights the importance of considering intermittent obstruction in pediatric hydrocephalus.
- Endoscopic fenestration is an effective treatment for hydrocephalus secondary to third ventricular choroid plexus cysts.
- Early diagnosis and intervention are crucial for favorable outcomes in infantile hydrocephalus.
Abstract:
The authors present the case of an 11-week-old girl in whom hydrocephalus developed secondary to intermittent obstruction of the third ventricle by a choroid plexus cyst. The patient presented to the emergency department at the authors' institution with a 1-day history of projectile vomiting, lethargy, and dysconjugate gaze. Hydrocephalus was confirmed on head CT. During hospitalization, the symptoms resolved with a decrease in ventricular size. One week later, the patient again presented with similar symptoms, and MR images with 3D-constructive interference in steady state sequences revealed that a cyst was blocking the third ventricle. The patient subsequently underwent endoscopic fenestration of the cyst with resolution of hydrocephalus and symptoms. The authors present a unique description of the diagnosis of intermittent obstructive hydrocephalus caused by a third ventricular region choroid plexus cyst in an infant.
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