Transient beta-catenin stabilization modifies lineage output from human thymic CD34+CD1a- progenitors

Jaris Valencia1, Carmen Hernández-López, Víctor G Martínez

  • 1Department of Cell Biology, Complutense University, Madrid, Spain.

Summary

Stimulating the Wnt signaling pathway in human thymic progenitors enhances natural killer (NK) cell production. This Wnt pathway activation also reduces the generation of myeloid lineage cells, including monocytes and dendritic cells (DCs).

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