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Published on: July 5, 2017
Exercise training as a treatment for chronic inflammation in the elderly
Barbara J Nicklas1, Tina E Brinkley
1J. Paul Sticht Center on Aging, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. bnicklas@wfubmc.edu
Persistent inflammation in older adults contributes to chronic disease and frailty. Emerging research suggests that increasing physical activity may be a viable strategy to reduce this inflammation, promoting healthier aging.
Area of Science:
- Gerontology
- Immunology
- Chronic Disease Epidemiology
Background:
- Persistent subclinical inflammation is a key factor in aging-related chronic diseases, sarcopenia, and disability among the elderly.
- The inflammatory pathway presents a significant therapeutic target for interventions aimed at mitigating age-associated decline.
- Understanding modifiable factors influencing inflammation is crucial for promoting healthy aging.
Purpose of the Study:
- To review emerging evidence on the role of physical activity in modulating chronic inflammation in the elderly population.
- To explore the potential of exercise interventions as a strategy to combat age-related inflammatory conditions.
Main Methods:
- This article synthesizes findings from recent research studies investigating the relationship between physical activity and inflammatory markers in older adults.
- A literature review approach was employed to highlight emerging data and trends.
Main Results:
- Emerging data indicate a strong association between increased physical activity and reduced levels of chronic inflammation in elderly individuals.
- Physical activity demonstrates potential as an effective, non-pharmacological intervention for managing inflammation in aging populations.
Conclusions:
- Increasing physical activity is a promising strategy for reducing chronic inflammation in the elderly.
- Targeting the inflammatory pathway through exercise may help prevent or delay the onset of age-related diseases and disability.
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