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A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

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Published on: May 22, 2018

Using the Generic Genome Browser (GBrowse).

Maureen J Donlin¹

¹Department of Biochemistry and Molecular Biology and Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.

Current Protocols in Bioinformatics

|December 4, 2009

Summary

This summary is machine-generated.

Generic Genome Browser (GBrowse) is open-source software for visualizing genomic data across various organisms. This update details software enhancements and data source updates for improved genomic research accessibility.

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Area of Science:

Bioinformatics
Genomics
Computational Biology

Background:

Genome browsers are essential tools for visualizing DNA and protein sequence data.
The Generic Genome Browser (GBrowse) is an open-source solution developed for the Generic Model Organism Database project.
GBrowse supports multiple model organisms and is widely used in genomic research.

Purpose of the Study:

To provide an updated overview of the Generic Genome Browser (GBrowse) software.
To detail recent software developments and release cycles.
To offer instructions for updating data sources with new NCBI files.

Main Methods:

GBrowse is configurable for displaying genomic sequence features for any organism.
The software is available for download and runs on Windows, Mac OS X, and Unix-type systems.
Active development ensures regular updates, approximately every six months.

Main Results:

GBrowse facilitates the visualization of genomic data, including DNA and protein sequences.
The software is adaptable for diverse organisms and is utilized for prominent model organisms.
Recent updates focus on improving data source management and integration with NCBI.

Conclusions:

GBrowse remains a valuable and actively developed open-source tool for genomic data visualization.
Regular updates enhance its utility and ensure compatibility with current genomic data standards.
The ease of installation and cross-platform compatibility make GBrowse accessible to a broad research community.