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Updated: Jun 18, 2026
Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
Published on: February 27, 2026
[Long-term results of surgical plus chemotherapy for stage I lung adenocarcinoma]
1Beijing Research Institute of Tuberculosis and Thoracic Tumors, Beliing Chest Hospital, Chest Surgery Department, Beijing 101149, China.
Objective:
Observe the effect of operation plus post-operative chemotherapy for long-term results of stage I lung adenocarcinoma.
Methods:
From January 1994 to January 2005, 427 patients with stage I lung adenocarcinoma underwent surgical resection therapy. The comparison of long-term survival rates was made between post-chemotherapy and surgical resection alone.
Results:
The analyses disclosed that the stage I a 1, 3, 5 and 10-year survival rate of post-chemotherapy was 100.00%, 92.34%, 86.17% and 74.82%, respectively, while in surgical resection alone was 96.63%, 88.11%, 79.52% and 65.85%, respectively. The stage I b 1, 3, 5 and 10-year survival rate of post-chemotherapy was 96.84%, 77.99%, 69.56% and 64.36%, respectively, while in surgical resection alone was 85.65%, 67.11%, 59.56% and 53.06%, respectively. There was statistically significant difference between 1 year survival rate of stage I a patients with post-chemotherapy and those with surgical resection alone (P < 0.05); 1 year survival rate of stage I b patients with post-chemotherapy and those with surgical resection alone (P < 0.01).
Conclusion:
The operation plus post-operative chemotherapy is better than surgical resection alone in stage I a and I b. Surgical plus post-operative chemotherapy mode is indispensable for better prognosis of stage I a and I b lung adenocarcinoma.