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Related Concept Videos

Probiotics01:22

Probiotics

Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
Microbiota Modulation by Antibiotics01:21

Microbiota Modulation by Antibiotics

Antibiotics have revolutionized modern medicine by saving countless lives from bacterial infections. However, their widespread use has inadvertently harmed the delicate balance of the human gut microbiota. The gut microbiota, a complex community of bacteria, archaea, viruses, and fungi, plays a vital role in regulating metabolism, immune responses, and maintaining intestinal health. Antibiotics, especially broad-spectrum types, disrupt this ecosystem by eradicating both harmful and beneficial...
What is the Immune System?01:38

What is the Immune System?

Overview
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Functions of the Gut Microbiota01:18

Functions of the Gut Microbiota

The gut microbiota includes trillions of microorganisms that colonize the human gastrointestinal tract, including bacteria, archaea, viruses, and fungi. This complex ecosystem plays a critical role in maintaining intestinal and systemic health. Most of these microbes inhabit the large intestine, establishing a relatively stable and diverse community that contributes to gut homeostasis through various metabolic, immunological, and protective mechanisms.Dominant bacterial phyla, such as...

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Related Experiment Video

Updated: Jun 18, 2026

Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells
06:07

Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells

Published on: June 13, 2020

Probiotics, immunity and exercise: a review.

N P West1, D B Pyne, J M Peake

  • 1Griffith Health, Griffith University, Southport, QLD, Australia.

Exercise Immunology Review
|December 5, 2009
PubMed
Summary
This summary is machine-generated.

Probiotic supplements may enhance gut and immune function for athletes. Further research is needed to determine optimal use for health and athletic performance.

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Last Updated: Jun 18, 2026

Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells
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Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
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Published on: July 31, 2019

Area of Science:

  • Sports Nutrition
  • Microbiology
  • Immunology

Background:

  • Nutritional strategies are crucial for athletic performance and overall health.
  • Probiotic supplements influence the gut microbiome, impacting immune and digestive functions.
  • The gut microbiota plays a vital role in immune system development, infection defense, and maintaining intestinal balance.

Purpose of the Study:

  • To explore the potential of probiotics in modulating gut and immune function.
  • To assess the benefits of probiotics for athletes facing physical and environmental stress.
  • To identify areas for future research regarding probiotic use in sports.

Main Methods:

  • Review of current literature on probiotics, gut microbiota, and exercise physiology.
  • Analysis of the interaction between gut microbes, host immunity, and physical stress.
  • Identification of knowledge gaps in probiotic research for athletes.

Main Results:

  • Probiotics modulate the intestinal microbial flora, potentially enhancing gut and immune health.
  • Probiotics may help regulate immune function disruptions caused by exercise.
  • Beneficial effects extend to respiratory, skin, and urogenital health.

Conclusions:

  • Probiotics show promise for improving athlete health and performance by supporting gut and immune systems.
  • Further research is essential to establish optimal probiotic dosages, species-specific effects, and clinical outcomes.
  • Probiotics could be a valuable tool for individuals under significant physical and environmental stress.