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Fatal Mycobacterium abscessus endocarditis misidentified as Corynebacterium spp
John C Williamson1, Todd A Miano, Michael R Morgan
1Department of Pharmacy, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA. johnwill@wfubmc.edu
Scandinavian Journal of Infectious Diseases
|December 5, 2009
Summary
Rapidly growing mycobacteria can be misidentified as corynebacteria in labs. Routine acid-fast staining is crucial for accurate diagnosis, preventing fatal outcomes like infectious endocarditis.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Diagnostics
Background:
- Rapidly growing mycobacteria and corynebacteria share microbiological characteristics.
- This similarity can lead to misidentification in clinical laboratory settings.
- Accurate identification is critical for appropriate patient treatment and outcomes.
Observation:
- A fatal case of infectious endocarditis is presented.
- The causative agent, Mycobacterium abscessus, was initially misidentified as Corynebacterium spp.
- The patient received treatment based on the incorrect identification.
Findings:
- Mycobacterium abscessus can mimic Corynebacterium spp. in standard laboratory tests.
- Misidentification can delay or alter appropriate antimicrobial therapy.
- The case highlights the potential for severe consequences due to diagnostic errors.
Implications:
- Routine acid-fast staining is recommended when Corynebacterium spp. are suspected or identified in blood cultures.
- Enhanced diagnostic protocols are needed to differentiate rapidly growing mycobacteria from corynebacteria.
- Improved laboratory identification strategies can prevent treatment delays and improve patient survival in cases of mycobacterial infections.
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