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Updated: Jun 18, 2026

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Isolation of Soluble and Insoluble PrP Oligomers in the Normal Human Brain
Published on: October 3, 2012
Interactions of ginkgolides A and B with a recombinant human prion protein
Dessislava Georgieva1, Lars Redecke, Martin von Bergen
1Institute of Biochemistry and Molecular Biology, University of Hamburg, Martin-Luther-King Platz 6, 20146 Hamburg, Germany.
Protein and Peptide Letters
|December 5, 2009
Abstract:
In the presence of ginkgolides A and B a recombinant human prion protein (90-231) is more susceptible to proteolysis, which is characteristic for the non-infective form of prion proteins and more thermostable than in the absence of ginkgolides. Probably, ginkgolides exert a neuroprotective effect through a rearrangement of the prion structure.
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