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Two new cytotoxic acetophenone derivatives from Euphorbia ebracteolata Hayata
Ning Zhang1, Hao Cai, BaoChang Cai
1Jiangsu Key Laboratory of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, PR China.
Abstract:
Two new acetophenone derivatives were isolated from the roots of Euphorbia ebracteolata Hayata, their structures were elucidated as 2,4-dihydroxy-6-methoxyl-methylene-3-methyl-acetophenone (1) and 2-dihydroxy-6-methoxyl-methylene-3-methyl-acetophenone-4-O-beta-D-glucopyranoside (2) on the basis of chemical and spectroscopic methods including (1)D- and (2)D-NMR techniques, and their cytotoxic activities were investigated by using the MTT method.