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Updated: Jun 18, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
Contemporary insights into the functional anatomy of the mitral valve
Jeffrey J Silbiger1, Raveen Bazaz
1Department of Cardiology, Mount Sinai Services at Elmhurst Hospital Center, Mount Sinai School of Medicine, New York, NY, USA. jeffrey.silbiger@mssm.edu
Abstract:
The mitral valve is a highly complex structure the normal functioning of which requires the coordinated interaction of the leaflets, annulus, chordae tendineae, and papillary muscles. Perturbations of any of these components can interfere with normal valve function. The integrity of the mitral valve is also essential to maintaining normal left ventricular geometry and function through closely coupled ventricular-valvular interactions. This review summarizes recent developments in our understanding of the anatomy and physiology of the mitral valve.
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