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Hybrid Printing for the Fabrication of Smart Sensors
Published on: January 31, 2019
CE-MALDI interface based on inkjet technology
Michael W Vannatta1, Colin D Whitmore, Norman J Dovichi
1Department of Chemistry, University of Washington, Seattle, WA, USA.
Electrophoresis
|December 5, 2009
Abstract:
An ink jet printer valve and a nozzle were used to deliver matrix and sample from an electrophoresis capillary onto a MALDI plate. The system was evaluated by the separation of a set of standard peptides. That separation generated up to 40 000 theoretical plates in less than 3 min. Detection limits were 500 amol for an ABI TOF-TOF instrument and 2 fmol for an ABI Q-TOF instrument. Over 70% coverage was obtained for the tryptic digest of alpha-lactalbumin in less than 2.5 min.
