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Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
Acute pancreatitis in pregnancy.
Capecomorin S Pitchumoni1, Balaji Yegneswaran
1Department of Internal Medicine, Saint Peter's University Hospital, New Brunswick, NJ 08901, USA. pitchumoni@hotmail.com
Acute pancreatitis (AP) in pregnancy is rare but serious, affecting maternal and fetal health. Advances in gastroenterology improve diagnosis and management, offering better outcomes for pregnant individuals with AP.
Area of Science:
- Gastroenterology and Obstetrics
Background:
- Acute pancreatitis (AP) is a rare complication during pregnancy, occurring in approximately 3 in 10,000 pregnancies.
- AP in pregnancy presents a spectrum from mild to severe, potentially involving necrosis and organ dysfunction.
- Physiological changes in pregnancy complicate the diagnosis and severity assessment of AP.
Purpose of the Study:
- To review the challenges and advancements in diagnosing and managing acute pancreatitis during pregnancy.
- To highlight the impact of pregnancy on AP presentation and interpretation of diagnostic tests.
- To emphasize the improved prognosis of AP in pregnancy with modern gastroenterological interventions.
Main Methods:
- Literature review focusing on AP in pregnancy.
- Analysis of diagnostic advancements in gastroenterology.
- Evaluation of therapeutic modalities for biliary pancreatitis.
Main Results:
- Pregnancy-related alterations affect diagnostic test interpretation and severity assessment.
- Modern diagnostic tools like endoscopic ultrasound and MRCP aid in early detection.
- Therapeutic options including ERCP, stenting, and laparoscopic cholecystectomy have improved management.
Conclusions:
- Acute pancreatitis in pregnancy requires careful consideration due to dual patient impact.
- Advances in diagnostic and therapeutic gastroenterology have significantly improved outcomes.
- Properly managed AP in pregnancy no longer carries a historically dismal prognosis.
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