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Published on: August 11, 2018
Effect of honey versus intergel in intraperitoneal adhesion prevention and colonic anastomotic healing: a randomized
1Port-Fouad General Hospital, Department of General Surgery, Port-Fouad, Port-Said, Egypt. alysaber54@gmail.com
Introduction:
Intra-abdominal adhesion formation and reformation after surgery are still an unavoidable event in spite of modern surgical techniques and are a cause of significant morbidity, resulting in infertility, pain and intestinal obstruction.
Aim:
To investigate the effect of honey in adhesion prevention and colonic anastomotic healing in rats.
Methods:
In the present study, 75 male Sprague-Dawley rats were used and divided into 3 groups for study: [25 rats for each], the intergel, honey and control groups. After the scheduled two-week's post-operative period, all survived rats were reopened for second-look laparotomy to detect the following parameters: a - adhesion, b - manometric study, c - histopathological study.
Results:
The author found that the total adhesion score, the manometric values and the histopathological study among the three studied groups showed statistically significant difference and in favor of the honey-treated rats.
Conclusion:
Honey surpasses the intergel for the healing power and adhesion prevention.
