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Indicators of a more complicated clinical course for pediatric patients with retropharyngeal abscess
Abdelaziz M Elsherif1, Albert H Park, Stephen C Alder
1Division of Otolaryngology/Head and Neck Surgery, University of Utah, 50 North Medical Drive, 3C 120, Salt Lake City, UT 84132, United States.
Insights
Pediatric retropharyngeal abscess (RPA) patients with airway obstruction or multiple abscess sites are more likely to have a complicated clinical course (CCC). Early identification of these signs is crucial for better patient outcomes.
Area of Science:
- Pediatric Otolaryngology
- Emergency Medicine
- Infectious Diseases
Background:
- Retropharyngeal abscesses (RPAs) are infections in the deep neck space.
- Identifying predictors of complicated clinical courses (CCCs) in pediatric RPA patients is essential for timely intervention.
Purpose of the Study:
- To determine clinical signs or symptoms associated with a more complicated clinical course in pediatric patients with retropharyngeal abscesses (RPAs).
Main Methods:
- Retrospective chart review at a tertiary care children's hospital.
- Evaluation of age, signs, symptoms, labs, imaging, treatment, pathogens, and hospitalization duration.
- Comparison of factors associated with complicated (CCC) versus smooth (SCC) clinical courses.
Main Results:
- Fifteen of 130 pediatric RPA patients experienced a CCC.
- Multiple abscess sites significantly correlated with requiring multiple procedures (p<0.001).
- Airway obstruction was a significant predictor of PICU admission/intubation in CCC patients (p<0.001).
Conclusions:
- Pediatric RPA patients with CCC are more likely to present with airway obstruction or multiple abscess sites.
- These findings aid in identifying high-risk patients needing closer monitoring and prompt management.
Objective:
Determine clinical signs or symptoms associated with a more complicated clinical course in patients with retropharyngeal abscesses (RPAs).
Design:
Retrospective chart review at a tertiary care level Children's hospital. Main Outcome Measures Age, presenting signs and symptoms, laboratory tests, imaging results, antibiotic therapy, surgical approach, pathogens isolated, and duration of hospitalization were evaluated to determine any factors associated with a more complicated clinical course (CCC).
Results:
Fifteen of one hundred thirty pediatric patients with RPA were identified with a complicated clinical course (CCC). Eight of the fifteen required more than one procedure before the abscess resolved. Patients with multiple abscess sites had a statistically significantly greater chance of requiring multiple procedures to clear the infections (p<0.001). Another seven presented with airway obstruction requiring an admission into the Pediatric Intensive Care (PICU) and/or intubation. All the patients requiring admission to the PICU presented with signs or symptoms of airway obstruction compared to ten of the one hundred fifteen patients (8.7%) with a smooth clinical course (SCC) (p<0.001). Five patients from the CCC group required a bronchoscopy to secure the airway; seven patients required intubation following incision and drainage of the abscess for an average of 5+/-3 days. There was no statistically significant difference between the two groups with respect to pathogens isolated, or antibiotics used.
Conclusion:
Our study suggests that patients with a CCC are more likely to present with airway obstruction or multiple abscess sites than patients with SCC.
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