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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: Jun 18, 2026

Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat

Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat

Published on: August 28, 2021

Functional MRI study of brain function under resting and activated states.

Wei Chen¹, Xiao Liu, Xiao-Hong Zhu

¹Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, 2021 6th Street SE, Minneapolis, MN 55455, USA. wei@cmrr.umn.edu

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

|December 8, 2009

Summary

Functional MRI (fMRI) using blood oxygenation level dependent (BOLD) contrast reveals brain activity. Researchers found a strong correlation between spontaneous brain activity and BOLD fluctuations, highlighting a close neurovascular relationship.

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Related Experiment Videos

Last Updated: Jun 18, 2026

Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat

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Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

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Area of Science:

Neuroimaging
Biophysics
Systems Neuroscience

Background:

Magnetic Resonance Imaging (MRI) techniques offer diverse contrasts linked to brain functions, electrophysiology, and diseases.
Recent advancements in MRI have led to functional MRI (fMRI) methods utilizing blood oxygenation level dependent (BOLD) contrast.

Purpose of the Study:

To apply advanced fMRI methods for detailed brain mapping.
To investigate the relationship between spontaneous brain activity and BOLD signal fluctuations.

Main Methods:

Utilized functional MRI (fMRI) techniques based on blood oxygenation level dependent (BOLD) contrast.
Applied fMRI for laminar-level brain activation mapping and functional connectivity analysis in resting-state brains.

Main Results:

Demonstrated the application of fMRI for mapping brain activation at the laminar level.
Showcased fMRI's utility in analyzing functional connectivity networks in resting brains.
Identified a strong correlation between spontaneous brain activity and BOLD signal fluctuations.

Conclusions:

The study confirms a tight neurovascular relationship.
BOLD-based fMRI is a powerful tool for understanding brain function and its underlying physiological correlates.