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Updated: Jun 18, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Development of central sleep apnea after maxillofacial surgery for obstructive sleep apnea
Shawn Corcoran1, Vincent Mysliwiec, Alexander S Niven
1Department of Medicine, Madigan Army Medical Center, Bldg 9040, Fitzsimmons Drive, Tacoma, WA 98335, USA. alice.uy@amedd.army.mil
Abstract:
Central sleep apnea is a rarely reported complication of surgery for obstructive sleep apnea (OSA). We report the case of a 38-year-old male who developed marked central sleep apnea 3 months after a maxillomandibular advancement for moderate OSA, which spontaneously resolved on his 6-month postoperative polysomnogram. Five prior cases of this postoperative complication have been reported in nonobese individuals after tracheostomy for OSA. Additionally, a recent study demonstrated that patients with atmospheric pharyngeal closing pressures are susceptible to unstable ventilation. We hypothesize that latent high loop gain from chronic OSA, coupled with atmospheric pharyngeal closing pressures, predisposed our patient to develop unstable ventilation after an abrupt postoperative change in his ventilatory load. Our case supports delaying postoperative polysomnography > or = 6 months in individuals at high risk for this complication.
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