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Identification of the base substitution responsible for the Ag(x/y) polymorphism of apolipoprotein B-100
1Department of Chemistry and Biochemistry, University of California, Los Angeles 90024-1570.
Abstract:
The identification of the base substitution responsible for Ag(x/y) completes the description of the antigen group polymorphisms associated with the apolipoprotein B polypeptide. Surprisingly, all five antigen group polymorphisms alter restriction endonuclease cleavage sites and have associated restriction fragment length polymorphisms, thereby providing a convenient alternative for antigen group phenotyping.