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Oogenesis

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...

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[Endometriosis].

Revista de medicina de la Universidad de Navarra·2009

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Related Experiment Video

Updated: Jun 17, 2026

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Published on: April 5, 2024

[Basic research into endometriosis. Are we going in the right direction?].

M García Manero¹

¹Departamento de Ginecología y Obstetricia, Clínica Universidad de Navarra, 31008 Navarra. mgmanero@unav.es

Revista De Medicina De La Universidad De Navarra

|December 10, 2009

Summary

Endometriosis, a common gynecological condition, may involve angiogenesis. Increased angiogenic factors in endometriosis patients suggest a potential target for new treatments and monitoring via serum markers.

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A Syngeneic Murine Model of Endometriosis using Naturally Cycling Mice

A Syngeneic Murine Model of Endometriosis using Naturally Cycling Mice

Published on: November 24, 2020

Area of Science:

Gynecology
Pathophysiology
Molecular Biology

Context:

Endometriosis is a prevalent gynecological disorder with unclear origins.
Retrograde menstruation is the leading hypothesis, but other factors influence susceptibility.
Angiogenesis plays a role in the development of endometriosis.

Purpose:

To explore the role of angiogenesis in endometriosis pathogenesis.
To identify potential serum markers for monitoring treatment response.

Summary:

Angiogenic factors are elevated in the peritoneal fluid, implants, and endometriomas of endometriosis patients.
This suggests that angiogenesis is a key process in the disease's development.
The study highlights the need for effective serum markers.

Impact:

Understanding the role of angiogenesis can lead to targeted therapies.
Development of optimal serum markers will aid in monitoring anti-angiogenic treatments for endometriosis.