Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

Antiasthma Drugs: β2-Adrenoceptor Agonists

Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce relaxation in these...
Antiasthma Drugs: Muscarinic Receptor Antagonists01:20

Antiasthma Drugs: Muscarinic Receptor Antagonists

Muscarinic receptor antagonists, also known as antimuscarinic agents, are a class of bronchodilators used to treat asthma, although they are more commonly used to treat COPD. They work by inhibiting the action of acetylcholine (ACh), a neurotransmitter, on muscarinic receptors found in the airways.
Antimuscarinic agents compete with ACh for the same binding site on the muscarinic receptors. By binding to these receptors, they inhibit the downstream effects of ACh and block the parasympathetic...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reply to: Is the role of eosinophils in refractory chronic cough truly dismissed? Mepolizumab reduced blood and sputum eosinophils, but not eosinophil-derived neurotoxin.

The European respiratory journal·2026
Same author

Ventilator Control Variables: Pressure Control, Volume Control, and Adaptive Targeting of Pressure Control.

NeoReviews·2026
Same author

Assessing the reliability of upper airway sampling for microbiological surveillance in cystic fibrosis.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2025
Same author

Mepolizumab for the treatment of refractory chronic cough in patients with eosinophilic airways disease (MUCOSA): a randomised, double-blind, parallel-group, placebo-controlled trial.

The European respiratory journal·2025
Same author

Reply to Zeng: the SOOTHE trial of camlipixant in RCC: a cautionary note on stratification and relevance.

American journal of respiratory and critical care medicine·2025
Same author

The NEuroCOUGH Chronic Cough Registry: a protocol for a pan-European observational study.

ERJ open research·2025

Related Experiment Video

Updated: Jun 17, 2026

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice
09:30

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice

Published on: October 3, 2025

Interrupting the cough reflex in asthma.

Jaclyn A Smith1

  • 1University of Manchester, UK. jacky.smith@manchester.ac.uk

Current Opinion in Allergy and Clinical Immunology
|December 10, 2009
PubMed
Summary
This summary is machine-generated.

Cough is an underappreciated yet significant symptom in asthma, often more bothersome than other common asthma issues. Further research and clinical attention are needed for this troublesome asthma cough.

More Related Videos

Methods for Detecting Cough and Airway Inflammation in Mice
04:33

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
05:56

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

Related Experiment Videos

Last Updated: Jun 17, 2026

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice
09:30

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice

Published on: October 3, 2025

Methods for Detecting Cough and Airway Inflammation in Mice
04:33

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
05:56

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

Area of Science:

  • Pulmonology
  • Allergy and Immunology
  • Respiratory Medicine

Background:

  • Cough is a primary symptom of asthma, yet often overlooked compared to wheeze or breathlessness.
  • Patient-reported impact of asthma cough is substantial, exceeding that of other symptoms like wheezing or sleep disturbance.

Purpose of the Study:

  • To review current understanding of cough in asthma.
  • To explore potential mechanisms triggering cough in asthma patients.
  • To evaluate current and future therapeutic options for asthma-related cough.

Main Methods:

  • Literature review of studies measuring cough objectively in asthma.
  • Analysis of potential cough triggers and pathomechanisms.
  • Assessment of existing and novel treatment strategies.

Main Results:

  • Objective cough measurements in asthma vary widely, from normal to chronic cough levels.
  • Triggers for cough in asthma remain poorly understood.
  • Current asthma treatments may not adequately address cough in all patients.

Conclusions:

  • Cough represents a significant clinical problem for a subset of asthma patients.
  • Asthma cough warrants increased attention in clinical practice and research.
  • Further investigation into cough mechanisms and targeted therapies is crucial.