[Morphological changes in the kidneys of pigs with an adenovirus infection]

Dystrophic and necrobiotic changes developed in the epithelium of the kidney tubuli of sucking pigs spontaneously and experimentally infected with adenoviruses. The epithelial cells showed hyperchromatosis of the nuclei, breaking up of the chromatin, and formation of nuclear function bodies. The swelling of the dystrophic cells produced certain amount of pressure on the adjacent capillaries. The pale colour of the kidney itselt was due to the dystrophy of the epithelium and the compression anemia. After the desquamation of the degenerated epithelial cells and their carrying away with the urine the capillaries became strongly dilatated. Groups of adjacent capillaries became macroscopically visible and assumed the appearance of a petechia. Edema in lymphoidcell proliferation were established in the interstitial tissue.