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Diet-induced acidosis: is it real and clinically relevant?
Joseph Pizzorno1, Lynda A Frassetto, Joseph Katzinger
1Bastyr University, Seattle, WA 98165, USA. drpizzorno@salugenecists.com
The British Journal of Nutrition
|December 17, 2009
Summary
Diet-induced acidosis, a long-debated concept, is supported by research. Differentiating acidosis from acidaemia clarifies that dietary factors can cause real, long-term health issues.
Area of Science:
- Physiology
- Nutrition Science
- Medical History
Background:
- The concept of diet-induced acidosis has been explored for over a century.
- Understanding physiological pH and its regulation is crucial in metabolic health.
- Historical perspectives reveal evolving scientific understanding and controversies surrounding acidosis.
Purpose of the Study:
- To review the historical understanding of physiological pH and acidosis.
- To examine the causes, recognition, and effects of acidosis.
- To propose differentiating 'acidosis' from 'acidaemia' to resolve confusion.
Main Methods:
- Historical literature review.
- Analysis of physiological support for acidosis concepts.
- Examination of research on pH normalization and dietary interventions.
Main Results:
- Diet-induced acidosis is a real phenomenon with significant long-term pathophysiological effects.
- Distinguishing acidosis from acidaemia clarifies research and clinical relevance.
- Evidence supports the clinical relevance of preventative measures and pH normalization.
Conclusions:
- Diet-induced acidosis, distinct from acidaemia, has demonstrable long-term health impacts.
- Recognizing and counterbalancing diet-induced acidosis through dietary means is clinically relevant.
- Clarifying terminology is essential for advancing research and clinical practice in this area.
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