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Updated: Jun 17, 2026
Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry
Published on: August 21, 2020
Hemodynamic monitoring in pigs undergoing orthotopic abdominal multivisceral transplantation
1Department of Anaesthesiology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Unlabelled:
Anesthesia for abdominal multivisceral transplantation (MVTx) is challenging. Surgical success depends on hemodynamic stability throughout organ removal from the donor and engraftment in recipients. The aim of the current study was to summarize our experience with anesthetic management including monitoring of hemodynamic changes in pigs during MVTx procedures.
Materials And Methods:
Ten male pigs were randomly divided into two groups: donors and recipients for five MVTxs. A pulmonary artery catheter (PAC), transesophageal echocardiography (TEE), and pulse indicator continuous cardiac output (PiCCO) were used intraoperatively in recipients to monitor hemodynamic changes.
Results:
Two recipients had cardiac arrest and died intraoperatively presumably due to hypovolemia. The data obtained by PAC and TEE from three successful cases showed huge changes in hemodynamics during the stages of organ removal and reperfusion after engraftment. Use of PiCOO in one of those three cases allowed successful fluid management, resulting in stable intraoperative hemodynamics.
Conclusion:
The anesthetic management for MVTx surgery was improved by PAC, TEE, and PiCOO monitoring.
