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Verbal fluency as a possible predictor for psychosis.

H E Becker¹, D H Nieman, P M Dingemans

¹Department of Psychiatry, Academic Medical Centre, Amsterdam, Netherlands. H.E.Becker@amc.uva.nl

European Psychiatry : the Journal of the Association of European Psychiatrists

|December 17, 2009

Summary

This summary is machine-generated.

Ultra high risk (UHR) patients who transitioned to psychosis showed impaired verbal fluency at baseline compared to those who did not. This finding may help predict psychosis transition in UHR individuals.

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Area of Science:

Neuroscience
Psychiatry
Cognitive Psychology

Background:

Neurocognitive abnormalities are common in schizophrenia patients and individuals at ultra-high risk (UHR) for psychosis.
Understanding these abnormalities is crucial for early detection and intervention.

Purpose of the Study:

To compare baseline verbal fluency performance in UHR patients.
To determine if verbal fluency differs between UHR patients who transition to psychosis and those who do not.

Main Methods:

Compared verbal fluency (semantic category) at baseline in UHR patients (n=47) with first-episode schizophrenia patients (n=69) and healthy controls (n=42).

Main Results:

UHR patients' verbal fluency scores did not significantly differ from first-episode schizophrenia patients.
Both UHR and schizophrenia patient groups performed significantly worse than controls.
UHR patients who transitioned to psychosis performed significantly worse on verbal fluency (semantic category) at baseline compared to non-transitioning UHR patients.

Conclusions:

Verbal fluency (semantic category) is impaired in UHR patients who transition to psychosis.
Baseline verbal fluency may serve as a predictor for psychosis transition in UHR individuals.