Related Experiment Video
Updated: Jun 17, 2026
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Optimal equations for describing the relationship between prostate volume, number of sources, and total activity in
Jesse N Aronowitz1, Jeff M Michalski, Gregory S Merrick
1Department of Radiation Oncology, University of Massachusetts Medical School, Worcester, MA, USA. jaronowitz@comcast.net
Objectives:
To determine whether there is an optimal type of mathematical equation for predicting seed and activity requirements for permanent prostate brachytherapy.
Methods:
Four institutions with extensive brachytherapy experience each submitted details of more than 40 implants. The data was used to generate power and linear equations to reflect the relationship between preimplant volume and the number of seeds implanted, and preimplant volume and the total implant activity. We compared the R and standard error of the generated equations to determine which type of equation better fit the data.
Results:
For the limited range of prostate volumes commonly implanted (20-60 mL), power and linear equations predict seed and activity requirements comparably well.
Conclusions:
Linear and power equations are equally suitable for generating institution-specific nomograms.
More Related Videos
09:49A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
08:54Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
Published on: May 8, 2018
Related Concept Videos
02:59Biological Effects of Radiation
01:06Three-Compartment Open Model